Santiago González graduated from the University of Santiago de Compostela (Spain) in the specialty of Marine Biology. He holds two PhD degrees, one in immunology from the University of Copenhagen (Denmark) and one in microbiology from the University of Santiago de Compostela. He continued his postdoctoral research in the Harvard Medical School, in Boston (USA) studying the immune response to vaccines. During this period, he was awarded the most prestigious European and Swiss grant (Marie Curie, Ambizione). In 2013 he joined the Institute for Research in Biomedicine in Bellinzona as a group leader studying pathogen-host interaction.

Tobias studied Veterinary Medicine at the Ludwig-Maximilians-Universität in Munich, Germany, where he also did his thesis at the Institute of Pharmacology and Toxicology. He joined Roche Diagnostics in 1997 and in 1998 transferred to Roche's Pharmaceuticals Division. From 1998 to 2007, he worked in Discovery Oncology as preclinical pharmacologist on several research projects. In 2007, Tobias moved to Large Molecule Research, heading the department of Immune Biology, overseeing the generation of new therapeutic proteins for all disease areas. In 2013, he transferred to Roche's Pharmaceutical Sciences organization and took over the role as Global Head of Comparative Pharmacology and Toxicology. In this role, he and his team are in charge of running Roche's animal facilities including the veterinary programmes and preclinical in vivo safety assessment in in-house in vivo studies. Tobias is representing Roche on several national and international animal welfare and 3Rs bodies e.g. at the Vfa and Interpharma. Since 2002, he serves on the Ethical Review Committee for Animal Experimentation at the Government of Upper Bavaria, since 2017, he has been appointed as member of the Swiss Federal Commission on Animal Experimentation. Tobias is a certified veterinarian in both pharmacology and toxicology and in laboratory animal science.

Prof. Nowak-Sliwinska is assistant professor at the Faculty of Science, Section of Pharmaceutical Sciences, and head of the research group Molecular Pharmacology. She is an expert in oncology and uses a combination of in vitro and in vivo approaches. She is very familiar with the 3Rs, was the recipient of the UNIGE 3R price in 2020, and has been a member of its jury for several years.

Elisabeth Stark has been full professor of Romance linguistics specializing in French since 1 February 2008. She studied Romance Linguistics and trained as an upper secondary school teacher of German and French at Ludwig-Maximilians-Universität (LMU) in Munich between 1988 and 1994, before gaining her PhD in 1996. Subsequently, she worked at the chair of Romance linguistics at LMU as a teaching and research assistant, and following her habilitation in 2003 as a senior teaching and research assistant. In the same year, she took over the substitute chair for French and Italian linguistics at the Department of Romance Literatures and Linguistics at Humboldt-Universität zu Berlin and in April 2004 was offered a full professorship for Romance linguistics at the Institute of Romance Languages and Literatures at Freie Universität Berlin. There she also served as Vice Dean of Studies of the Department of Philosophy and Humanities before accepting the professorship in Zurich in 2008. Her research and teaching interests include the structure of nominal expressions and their typological implications in Romance languages, language variation, especially language use and grammar in new digital communication forms, and syntax, in particular word order and information structure, congruence phenomena, syntax theories and their application to Romance languages.

Michael Walch holds currently a full professor position of Anatomy and Cell Biology in the Department of Oncology, Microbiology and Immunology and serves as the Vice-Dean of the Faculty of Science and Medicine at the University of Fribourg. Professor Walch is also founding member and Vice-President of the Academia of Sciences in Liechtenstein. He received his M.D. degree and attended the Postgraduate Course in Experimental Medicine and Biology at the University of Zurich For continuative postdoctoral training, he joined the Department of Molecular and Cellular Medicine at Harvard Medical School and Boston Children`s Hospital. His research focuses on microbial immunulogy with a special interest in cytotoxic effector molecules in antimicrobial defense at the cellular and system level.

Hugues Abriel studied life sciences at the Swiss Federal Institute of Technology in Zurich (ETHZ, 1989) and medicine at the University of Lausanne in Switzerland (MD, 1994). He received a Ph.D. degree in Physiology from the University of Lausanne (1995) and has spent two years as a research scientist at Columbia University in New York, USA. Hugues Abriel has been a Group Leader (2002-2009) at the Department of Pharmacology and Toxicology at the University of Lausanne, thanks to a professorship from the Swiss National Science Foundation (SNSF-Professor). From 2009 until 2016, he was the Director of the Department of Clinical Research at the University of Bern. Since October 2016, he is Co-Director of the Institute of Biochemistry and Molecular Medicine of the University of Bern, as well as Professor of Molecular Medicine. From 2012 until 2020, he was a member of the SNSF research council and was the president (2018-2020) of the division biology and medicine. He is the Director since 2015 of the SNSF-funded research network NCCR TransCure. His research work focuses on the roles of ion channels in human diseases (channelopathies). Currently, he is mainly exploring the genetic, molecular, and cellular bases of cardiac arrhythmias. From November 2020 to August 2021, he took an academic sabbatical to visit the universities of Kinshasa (Democratic Republic of the Congo) and Fez (Morocco) in French-speaking Africa to gain new perspectives and broaden his academic experiences. Since 2022 he is the vice-rector for research at the University of Bern.

Christian was born on July 17, 1972 in Bonn, Germany and studied Chemistry at the Westfälische Wilhelms Universität Münster, Germany. After his graduation, he spent six years as a postdoctoral fellow in the laboratory of Prof. Markus Stoffel at the Rockefeller University in New York, USA. In 2007 he moved to the ETH Zurich and in 2008 he was appointed Assistant Professor for Obesity Research. His research focuses on elucidating the molecular mechanisms underlying the altered adipocyte differentiation and maturation associated with obesity and other metabolic disorders. Christian Wolfrum has received the several honors, including the H.P. Kaufmann Award (2000), the Young Investigators Award by the EFSTL (2004), the Starting Independent Researcher Grant from the ERC (2008) and the Rössler Award (2014).

Urs Hilber conducted studies of biology (botany, zoology and chemistry) at Uni. Basel, ETHZ und UK. He obtained a PhD at Uni. Basel in collaboration with Agroscope, Ciba-Geigy, and conducted a post doc at Cornell University NY, in the United States. At the Swiss Society for the Chemical Industry (SGCI, today scienceindustries) he supervised the agricultural section and its subgroups and also acted as Vice Director and Director of Agroscope. Since 2007, he is on the management board of ZHAW where he has been Head of R&D from 2011 to 2017. He is currently the Dean of the School Life Sciences and Facility Management.

Liliane Michalik joined the University of Lausanne in 1994, after obtaining her PhD in Life Sciences from the University of Strasbourg, France. Since then, she has been active in biomedical research, with the overall goal of understanding skin responses to injuries and to UV-ray exposure. Liliane Michalik is also committed to education and public outreach. Between 2011 and 2021, she was vice-Director and then Director of the School of Biology of the Faculty of biology and Medicine of the University of Lausanne. In August 2021, she joined the Rectorate of the University of Lausanne as Vice-Rector for "Equality, Diversity and Careers ».

Following her degree in veterinary medicine from the Ludwig- Maximilian-University Munich, Germany, in 1994 she worked as an assistant veterinarian in different animal veterinary practices and clinics, Switzerland and opened her own small animal veterinary practice in 1996. She received her PhD in Veterinary Medicine from the University of Zurich in 2000. Julika Fitzi-Rathgen used to work as consultant and investigator in clinical and preclinical research between 2000 and 2004. In 2014, she graduated with a master's degree in law from the University of Bern and in 2016; she completed studies in mediation and conflict resolution at the University of Fribourg. Since 2008, she has acted as head of the unit Animals in Research & Genetic Technology as well as for the special animal welfare field of Dogs & Veterinary Consulting at Swiss Animal Protection SAP.

Falko Schlottig studied chemistry at Technical University Bergakademie Freiberg and completed his PhD in physical chemistry in 1996 at the TU Chemnitz. In 1996, he started as a postdoc at ETH in the group of Prof. Textor and at Alusuisse. Since then gained many years of experience in management positions in international life sciences companies. In addition to various positions as head of research and development departments in the industrial field, he completed an EMBA at the University of St. Gallen. He also advises young life sciences companies and acts as a start-up founder. He has been director of Life Sciences for the FHNW since 2015.

René P. Buholzer is CEO of Interpharma. He holds a PhD from the University of St. Gallen, where he was a lecturer for more than a decade. Prior to joining Interpharma, he has been for more than 10 years Global Head of Public Policy and Sustainability at Credit Suisse, where he led a global team in Zurich, London, Hong Kong and New York. Before joining Credit Suisse, René Buholzer was an Executive Board member of economiesuisse in charge of environmental, ICT and regional policy. He also worked as a management consultant in Prague and as a teaching assistant at the University of St. Gallen. He has published in the fields of public policy, economic policy and Swiss- EU relations. Within the University of St. Gallen René Buholzer currently serves as President of the Board of Governors at the Swiss Institutes for International Economics and Applied Economic Research. He is Council member of IFPMA, the global association of the pharmaceutical industry and serves at the Foundation Board of Switzerland Innovation. He is also a board member of the Club politique de Berne, board member of the Dr. Heinrich Wachter Stiftung, Councillor at the British Swiss Chamber of Commerce and board member of the Alumni Council of the Swiss American Foundation.

Department of Biomedicine Prof. Rolf Zeller is Full Professor in Anatomy and Embryology in the Department of Biomedicine at the University of Basel. The main research topics of his group include genetic and systematic analysis of the signal-antagonist interactions and auto-regulatory feedback loops that control vertebrate organogenesis. He uses mouse molecular genetics in combination with cell biochemistry and databased simulations of complex regulatory system to study fundamental questions of embryonic development. Rolf Zeller is also President of the Basel Declaration Society, which promotes ethically responsible research with animals and openness in communication and publication; member of the National Research Council of Switzerland (Division III: Biology and Medicine); elected Member of EMBO; and Fellow of the Royal Society of Biology (UK).

Member of the Committee for Science, Education and Culture and of the delegation for the relations with the French Parliament. Simone de Montmollin began her career in the medical field, working for the European Society of Cardiology before founding her own medical communications company, Götz & Cie Cardio Diffusion, in 1991. De Montmollin left the medical field to become an oenologist, and served as the director of the Swiss Union of Oenologists, worked as a communications specialist at Agroscope, and served as chairwoman for the 42nd World Congress of Vine and Wine in Geneva. In 2008 she was elected, as an Independent, to the Geneva Constituent Assembly. She later joined FDP The Liberals and was elected to the Grand Council of Geneva, serving from 2013 to 2018. In her last year on the council, she was the president of the Committee for Environment, Agriculture, and Management. In 2019, de Montmollin was elected to the National Council, where she is a member of the Committee for Science, Education and Culture and the Delegation for Relations with the French Parliament. She has served as a member of the 3RCC Strategic Board representing the members of federal councils since May 2021.

Dr. Jenny Sandström is a molecular biologist by training and originates from Umeå (Sweden). She obtained her PhD at the Eberhard-Karls University of Tübingen University, followed by postdoctoral research in neurotoxicology at the University of Lausanne. In 2015 she joined the Swiss Centre for Applied Human Toxicology working with regulatory toxicology research, research programme coordination and development of continuing professional education. Since October 2020, she is leading the Swiss 3Rs Competence Centre.

Dr. Armand Mensen joined the Swiss 3RCC in August 2018 as the first Scientific Officer. Armand spearheads the development, implementation, and management of the Centre's funding scheme. With a Ph.D. in Psychology, emphasizing neuroimaging, sleep, and neurological disorders, he embarked on an academic journey with Postdocs in Madison, Liege, Amsterdam, and the University Hospital in Bern. Before his current role, Armand exclusively pursued an academic career. Armand's academic expertise lies in the neuroscience of sleep and neurological disorders, as well as experimental design and data analysis. He earned his Masters in Edinburgh, Scotland, and completed his Ph.D. in Zurich, Switzerland. Born in Holland and raised in Canada and Spain, Armand brings a diverse background to his work. Beyond the 3RCC, he is also an American Football Coach.

Kathryn Sadowski joined the 3RCC in February of 2021. She is a CPA qualified accountant with more than fifteen years experience in the full finance function in both commercial and not for profit organisations. Her senior finance roles at organisations such as Great Barrier Reef Foundation (Australia) was the perfect compliment to her current role in understanding the complexities of grant management and associated compliance and governance.

Dr. Jessica Lampe joined the Directorate in October 2022 as the Communications Manager. With a passion for science communication, she has an interdisciplinary academic and industry background that encompasses psychology, applied animal behaviour and welfare, biomedical research, and humanities. She is a TedX speaker and Forbes 30-under-30 awardee (2018).

Dr. Antoine Champetier joined the Directorate in September 2022 as scientific officer and data analysist. His work focuses on the monitoring mandate of the Center and he supports its efforts to improve our understanding of the trends and drivers of animal uses in research and development. He received his PhD in agricultural and resource economics from the University of California, Davis in 2010 and has since worked as an independent researcher, lecturer and consultant.

Dr. Robbie I’Anson Price joined the 3RCC Directorate in October 2023 as a scientific officer. He is a passionate science communicator, filmmaker and educator and has founded several science communication projects in Switzerland. As an educator he has developed and taught courses at EPFL, the University of Geneva and the University of Zürich, among others. With the 3RCC Robbie combines his passion for science engagement with the important challenges surrounding the 3Rs. His work focuses on co-producing digital media to support the communication of 3RCC projects and co-creating inspiring events that progress the cause.

Aude Rapet joined the Directorate in October 2023 as a Scientific Officer, where she oversees the education mandate. Deeply fascinated by the interface between engineering and biology, she specialized her engineering degree in biomechanics. During her studies, she has participated in multidisciplinary research projects across various academic groups worldwide. Her enthusiasm for the potential applications of microfluidics led her to work as a bio-engineer in a cutting-edge start-up, focused on the development of organ-on-chip platforms as alternatives to animal testing. Now, at the Swiss 3RCC, she can pursue her engagement to advance the 3R principles by leveraging education.

Rameez Subhan joined the Directorate in June 2025 as a Grant Officer and has nearly a decade of research grant management experience, built up across several British universities. At the 3RCC, Rameez supports the funding mandate by overseeing the full grant lifecycle, from application to completion. He combines scientific expertise from his degree in Biological Sciences with extensive administrative experience to help strengthen 3RCC’s research funding programme and its support for 3Rs research.

Coming soon

Emiliano Pasquini earned his master's degree in Medical Biotechnology from La Sapienza University in Rome, where he focused on liver zonation. He also completed a postgraduate specialization in Business Management Systems, during which he gained extensive experience in drafting SOPs and conducting external audits. In 2015, Emiliano moved to Bellinzona to work as a Laboratory and In Vivo Operations Manager at IOR in Andrea Alimonti’s Molecular Oncology Lab. As a Study Director, he is responsible for all in vivo experiments, ensuring both scientific rigor and regulatory compliance. He serves as Co-Responsible for the Imaging Facility at IOR and is also responsible for performing and teaching experimental procedures, managing transgenic mouse lines, and overseeing animal resources. Additionally, Emiliano is one of the founding members of the Culture of Care (CoC) group at Bios+.

Stefanie Hiltbrunner studied biology with a focus on immunology at the ETH Zurich and completed her PhD at the Karolinska Institute in Stockholm, specializing in cancer vaccines. After a short postdoctoral period at the University of Zurich, she joined the University Hospital of Zurich as a senior scientist in clinical and translational cancer research. Her research focused on the tumor microenvironment and immune response mechanisms to immunotherapy in lung cancer patients. She also managed the biobank for a phase II clinical trial and gained extensive experience working with human samples. Following the relocation of the research group to the University of Fribourg in 2022, Stefanie joined ETH Zurich as an Animal Welfare Officer in January 2024.

Silvana Libertini obtained a PhD in “Molecular Oncology and Endocrinology” from the University of Naples “Federico II” (Italy) after which she moved to the Beatson Institute for Cancer Research in Glasgow (UK), where she studied DNA damage and tumorigenicity. Since 2015, Dr Libertini has been working at the PreClinical Safety Department in Novartis focusing on the development of new methods to assess the genotoxic risk associated with the use of advanced therapy products (mainly CAR T cells, CRISPR/Cas9, AAV based gene therapy). Due to her interest in state-of-the-art in vitro models, Silvana represents Novartis in several NC3Rs led CRACK-IT challenges (InMutaGene, CleanCut, Transgene track, T-Alert) and in HESI CT-TRACS.

Elsa Giobellina completed her training at the University of Lausanne and the Vaud University Hospital Center (CHUV). After obtaining a Master of Science in Medical Biology in 2012, followed by a PhD in Neuroscience in 2016, she undertook training as an experiment supervisor. She then joined the Consumer and Veterinary Affairs Service (SCAV) in Epalinges as a microbiology and molecular biology laboratory technician. She was appointed Deputy Director of Animal Experimentation and Animal Welfare Officer at the University of Geneva (UNIGE) in December 2017.

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Markus Rimann studied Biology with specialization in Biotechnology at the ETH Zurich. After PhD completion at the Department of Materials, ETH Zurich, he did a Postdoc at the University of Zurich. For more than 11 years, he is working at the Zurich University of Applied Sciences (ZHAW) leading the group 3D Tissues and Biofabrication. His research is focusing on advanced 3D cell culture systems so called microphysiological systems (MPS), using different technologiessuch as bioprinting. He is leading the international network TEDD (Tissue Engineering for Drug Development and Substance Testing), with the goal of implementing MPS in routine processes in industry to reduce and replace animal experiments.

Joachim Köser studied Biology at the Heidelberg University and did his PhD in Cell Biology at the German Cancer Research Center. Following a Post-Doc at the Biozentrum in Basel and a position in a biosensor Start-Up company he joined the FHNW where he works on different topics in Nanotechnology, Cell-Materials interactions, Tissue Engineering, in vitro Diagnostics and Microphysiological Systems.

Bjoern Lex studied biology at the University of Tuebingen (Germany) and received his PhD in Neurobiology from the University of Stuttgart (Germany), specializing in the field of behavioral neuropharmacology of learning and memory systems. He did a postdoc at the Werner Siemens Imaging Center (University of Tuebingen), before joining Novartis as an Animal Welfare Officer in 2010. Since July 2020 he is the Animal Welfare Officer of Roche (Basel). Currently he is also the vice chair of the Swiss Animal Welfare Officer Network.

Andrina Zbinden is a veterinarian and did her doctoral thesis in the Division of Animal Housing and Welfare at the Vetsuisse Faculty in Bern, she promoted in behaviour and housing of golden hamsters. After a PostDoc position in the same Division she left the dedicated animal welfare area. In 2011 she started as Animal Welfare Officer at the University of Fribourg. Since 2017 she is member of the SGV Board, Schweizer Gesellschaft für Versuchstierkunde.

Hanno Würbel studied biology at the University of Bern in Switzerland and graduated with a PhD from the ETH Zurich. He continued research as a postdoc at Bristol University, ETH Zurich, and University of Zurich before being appointed Professor of Animal Welfare and Ethology at the University of Giessen in Germany in 2002. In 2011, Hanno Würbel moved back to his alma mater to take up to the new Chair for Animal Welfare at the University of Bern. His research focuses on the plasticity of the brain and behavior and its implications for the welfare of animals in captivity and for the scientific validity of animal research. For his research on refinement of animal experiments he obtained several research awards and funding from the European Research Council.

In his current role, Daniele Roppolo is responsible for the supervision of the various facets of animal experimentation at the University of Geneva including education, infrastructure, legislation, communication and promotion of the 3Rs. He works in close collaboration with the Animal Welfare Officer, the Vice-rector for animal experimentation, the Academic Director of animal experimentation and the many laboratories dealing with 3Rs and animal experimentation. As 3RCC node coordinator, he contributes to the proposals of projects, collection of data and implementation within the University of Geneva. Daniele Roppolo holds a PhD in biology and has long experience in research.

Anke Rohlfs holds a veterinary and PhD degree from the Veterinary School Hanover, Germany. Following two postdocs in neuropharmacology at the Battelle Institute, Geneva, and Novartis Pharma, Basel, Anke has gained over 20 years of experience in animal experimentation in the pharmaceutical industry, with six years as study director and 20 years as animal welfare officer, regionally and globally. Her special expertise is in international regulations and standards for animal welfare in animal-based research; establishment, and promotion of AW & 3R programmes; ensuring compliance and risk management. Anke Rohlfs joined the Animal Facilities & Welfare team of the University Basel in October 2017. Since 2018 she is the Coordinator 3R at the university.

Since September 2018 Anne Planche is the coordinator of the Swiss Animal Facilities Network (SAFN), a network of universities with animal facilities. SAFN deals with issues related to animal experimentation, animal husbandry and animal welfare. It supports universities’ communication in animal experimentation, it takes position on legislation and regulation concerning animal experimentation, and it is a partner of the Federal Food Safety and Veterinary Office (FSVO) and the cantonal authorities. SAFN will provide the Executive Board of the 3RCC with its expertise in animal husbandry and wishes to contribute in particular to the strategy for reduction.

Stéphanie Claudinot was trained as a marine and invertebrate biologist and obtained her PhD in Developmental Biology from the University Paris VI with a thesis on hair follicle stem cells in rats. After 15 years of post-doctoral fellowships on epithelial stem cells in the rodents at the Ecole Polytechnique Fédérale de Lausanne (EPFL) and the Centre Hospitalier Universitaire Vaudois (CHUV), she now studies skin parasitology and inflammation in mice. She joined the 3RCC in August 2018.

Christelle Cadilhac studied animal physiology and received her PhD in Neurosciences from the University of Montpellier (France), where she studied cerebellum development in mice. She continued research as a postdoc at the University of Geneva where she combined multiple transgenic mouse lines and transcriptomic approaches to highlight neuronal diversity. Since September 2021, Christelle Cadilhac is the coordinator of the Lemanic Animal Facilities Network that aims at coordinating and optimizing all the activities related to animal experimentation such as education and communication regarding the five main lemanic institutions (UNIL, CHUV, EPFL, UNIGE and HUG).

Philippe Bugnon studied veterinary medicine and obtained a doctorate at the University Bern on the topic of rabies vaccination evaluation and eradication of rabies in Switzerland. He worked in different academics positions performing research and animal experimentation in skin wound healing and liver regeneration and was responsible for rodent facilities at the Swiss Federal Institute of Technology Zurich. Since 2010 he is the head of the education in laboratory animal science at the Institute for Laboratory Animal Science at the University of Zurich. Additionally he is involved in several associations and foundations in the laboratory animal science field. He is also the current president of the Federal Committee on Animal Testing EKTV-CFEA.

Alexandre Widmer studied biology in Neuchâtel, then obtained a PhD in Physiology and Biophysics at Dalhousie University, Canada, where he worked on electrophysiological characterization of spider mechanosensory neurons. With support from the SNF, he furthered his expertise in invertebrate sensory physiology, genetics and behaviour during his postdoctoral training at the IMP, Vienna, working on Drosophila courtship. He finally trained on a mouse model of olfaction at the University of Geneva, funded by a Marie Curie fellowship for advanced researchers. After a scientific support role in a commercial setting, he joined the EPFL Center of Phenogenomics in 2020 as 3RCC coordinator.

Homare Yamahachi finished his Biology degree at the University of Buenos Aires in Argentina before obtaining his PhD in Charles Gilbert lab at The Rockefeller University in New York City. During his doctoral studies, Homare discovered that changes in sensory experience alter neuronal structural plasticity in vivo using viral vectors and two-photon microscopy. During his postdoc at the Moser lab in Norway, Homare studied how the brain computes space to navigate the world. He then studied social communication in birds with an emphasis on animal welfare in the Hahnloser lab at the University of Zurich and ETHZ. Homare is currently involved in implementing the 3Rs Principle of Animal Experimentation (Replacement, Reduction, Refinement) within the University of Bern.

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Katja Schenke-Layland (born Eisenach, Germany, March 21, 1977) is the Professor of Medical Technologies and Regenerative Medicine, Institute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine at the University of Tübingen. She is the Director of the NMI Natural and Medical Sciences Institute at the University Tübingen in Reutlingen, Study Dean of Medical Technologies at the University of Tübingen, and Founding Director of the Institute of Biomedical Engineering at the Medical Faculty of the University Tübingen. She is also the Founding Director of the 3R Center for In Vitro Models and Alternatives to Animal Testing Tübingen. She is also the Director of The Natural and Medical Sciences Institute (NMI) at the University of Tübingen in Reutlingen. Currently, her research lab at the University Tübingen focuses on the translation of human development into clinically relevant biomaterials and regenerative therapies, and the development of diagnostic tools to assess (stem) cell states, discover therapeutic candidates and diagnose diseases. She leverages her appointments to bridge the gaps between science and industry to drive viable health care solutions, particularly at the NMI where they focus on supporting local SMEs.

Prof. Robert Hindges leads the Neural Connectivity and Visual Function Lab. He focuses on the development and function of connections in the brain and investigates the molecular and cellular mechanisms that control the establishment of neural circuits, in particular during the process of guiding cells to the correct place and subsequently deciding with which other neurons in the network they should connect. A large part of his work is done in the vertebrate visual system. His lab is particularly interested in studying candidate genes that have been linked to neurodevelopmental disorders, including schizophrenia, bipolar disorder, and major depression. Prof. Hindges is a member of the Centre for Developmental Neurobiology and the MRC Centre for Neurodevelopmental Disorders. He is also the Academic Head of the Genome Editing and Embryology Core Facility (GEEC) at King’s College, which offers state-of-the-art technologies to the research community.

Jan van der Valk is trained in biomedical sciences. He was involved in establishing the Netherlands Centre for Alternatives to Animal experiments in 1994 and has been involved in stimulating the development, acceptation and implementation of 3Rs models ever since. Since 2010, he coordinates the 3Rs-Centre Utrecht Life Sciences (www.uu.nl/3rsCentreULS) at Utrecht Life Sciences, which include Utrecht University and University Medical Centre Utrecht. He is involved in several 3Rs education and training programs. The 3Rs-Centre ULS supports the 3Rs, among other activities, by the 3Rs-database program (https://www.uu.nl/en/3rsdatabases). He is also member of the project team of U-AIM (Utrecht Advanced In Vitro Models), a hub aimed to replace animal experimentation with advanced in vitro and in silico methods. There is a close collaboration from the 3Rs-Centre ULS with the Utrecht Animal Welfare Body.

Paul Flecknell is a graduate of Cambridge Veterinary School and has specialist qualifications in veterinary anaesthesia and analgesia and in laboratory animal medicine, and a PhD in Physiology. He managed the research animal facilities at Newcastle for over 30 years until his retirement in 2017. He is currently an Emeritus Professor at Newcastle University. He has been working in the field of laboratory animal science and animal welfare since 1977. He has been developing teaching and training resources to promote best practice in animal anaesthesia and analgesia for over 30 years, and he is currently co-developing a series of e-learning programmes. He has extensive knowledge and experience of all aspects of the use of animals in biomedical research. He has worked with many professional and public bodies including the U.K. NC3Rs, the Swedish 3Rs funding panel, the Doerenkamp-Zbinden foundation and other groups to promote the 3Rs nationally and internationally. He now works as a freelance consultant, and his company (FLAIRE consultants) provides training and training resources for all those involved in in vivo research.

Anna Olsson's background is in animal science, ethology and animal welfare. She has been a full-time researcher since 1996, working with farm animals, laboratory animals and recently also companion animals. Since 2005, she coordinates a research group at the Institute for Molecular and Cell Biology (now part of i3S – Institute for Research and Innovation in Health) at the University of Porto. Her research focuses on behaviour and welfare of animals used in research and on animal research ethics. She is engaged in the international animal welfare research community in a number of ways, as co-editor for the textbook Animal Welfare, as academic editor for the journal PLOS ONE, as Trustee for Universities Federation for Animal Welfare and Humane Slaughter Association and now also as a member of the Scientific Advisory Board for the Swiss 3R Competence Center. This engagement reflects her strong belief in that human and non-human animals can live together in mutual benefit, and in the importance of knowledge to improve the way we keep animals. Finally, she is the author of the science communication blog Animalogues about animal welfare and animal ethics research.