by robbie ianson price | Jul 8, 2025 | Funded Projects
BACKGROUND Since 2014, Marsano group has developed several functional healthy and disease (hibernate myocardium-like or scar-like) engineered 3D micro- and macro-scale cardiac tissues. Although neonatal cardiac cells were predominantly used to obtain...
by robbie ianson price | Jul 8, 2025 | Funded Projects
BACKGROUND Fragile X syndrome is a condition that affects the development of the nervous system. It is a leading cause of autism, a prevalent neurodevelopmental condition that is currently untreatable. Fragile X animal models display deficits at the level of neuronal...
by robbie ianson price | Jul 8, 2025 | Funded Projects
BACKGROUND The Blood-Brain Barrier is a structure between the central nervous system (CNS) and the bloodstream, whose main role is to protect the CNS from toxic compounds while allowing the passage of nutrients. Importantly, due to the activity of drug efflux...
by robbie ianson price | Jul 8, 2025 | Funded Projects
BACKGROUND In precision oncology, single drug treatment often leads to acquired resistance and tumor relapse. Novel drugs to overcome resistance are in development. Unfortunately, there is a substantial number of animals used, costs involved and high failure...
by robbie ianson price | Jul 8, 2025 | Funded Projects
BACKGROUND Biomedical research relies on genetic manipulation of animals, particularly mice, as experimental models to mimic human diseases and study their mechanisms. A widely used system relies on the use of the enzyme Cre recombinase. A variant of this enzyme,...
