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Algorithmic Breeding Planning

by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects

An automated system for the assessment of pain and wellbeing in laboratory mice

An automated system for the assessment of pain and wellbeing in laboratory mice

by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects

APPLICATION ABSTRACT Monitoring the well-being of mice in research labs is often overlooked, and current methods rely on subjective observations, leading to potential biases and variations between different observers. Recent advancements in machine vision and learning...
Evaluation of environmental enrichments for mice

Evaluation of environmental enrichments for mice

by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects

BACKGROUND High-quality environmental enrichment ameliorates the quality of life of laboratory mice. Commercially validated enrichment should still be evaluated in house. Three environmental enrichments are evaluated though behavioural observation in laboratory mice....
Providing immunocompetence to human microtissue bladder models

Providing immunocompetence to human microtissue bladder models

by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects

BACKGROUND At my home lab, we established several human bladder microtissue models to understand host-uropathogen interactions in patient-like scenarios, to be tested for novel urinary tract infections (UTI) therapeutics. However, they still lack the immune cell...
Implementation of the liver fibrosis AOP in a novel liver chip

Implementation of the liver fibrosis AOP in a novel liver chip

by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects

BACKGROUND Our research group aims to implement various biological questions and models in microphysiological systems (MPS). We have established an iPSC-derived blood-brain barrier on a Mimetas chip (Burgio et al., 2023) and an in vitro kidney model on the Vitrofluid...
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