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Refining intracerebral administration of drugs with sonoporation-activated microbubbles

by robbie ianson price | Jul 7, 2025 | Funded Projects

BACKGROUND Intracerebral administration of central nervous system (CNS) active agents through intracranial surgery is a widely used procedure in modern neuroscience. The discovery of new therapeutic treatment options for CNS diseases or the use of viruses to study the...
Identifying new regulators of cell invasion in colorectal cancer using the Drosophila adult intestine

Identifying new regulators of cell invasion in colorectal cancer using the Drosophila adult intestine

by robbie ianson price | Jul 7, 2025 | Funded Projects

BACKGROUND Colorectal cancer (CRC) is a cancer of the colon and the rectum. It is the third most prevalent cancer worldwide and is the fourth most common cause of cancer-related deaths. If the cancer is localised, the five-year survival rate is 90%; if the cancer has...
Reducing the need for lethal health monitoring in trout

Reducing the need for lethal health monitoring in trout

by robbie ianson price | Jul 7, 2025 | Funded Projects

Proliferative Kidney Disease (PKD) is a deadly parasitic fish disease that is classified as reportable and that has to be monitored in Switzerland. For this purpose, 15’500 potentially healthy pre-reproductive brown trout were electrofished and euthanized since...
Engineering a novel cell-based model for assessing materno-fetal drug transfer during pregnancy

Engineering a novel cell-based model for assessing materno-fetal drug transfer during pregnancy

by robbie ianson price | Jul 7, 2025 | Funded Projects

BACKGROUND The human placenta is a vital organ that acts as a barrier between the circulation of the mother and the growing fetus. It represents the interface between specialised placental cells called trophoblasts and fetal endothelial cells of the micro-vessels....
Development of a platform for GU cancer patient-derived organoids

Development of a platform for GU cancer patient-derived organoids

by robbie ianson price | Jul 7, 2025 | Funded Projects

BACKGROUND Understanding and overcoming cancer therapy resistance is a major overarching goal of our precision oncology program at the University of Bern. One of the greatest hurdles is the lack of reliable model systems to untangle resistance on a patient to patient...
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