by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects
BACKGROUND Transgenic animals represent a powerful tool in Biology that enables the study of cellular and molecular mechanisms, the modeling of diseases, and assessing the efficacy of therapeutic interventions. Among all mammalian species, the mouse stands out as a...
by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects
AIMS Duchenne muscular dystrophy is a fatal genetic disorder affecting boys. Finding a cure relies on dystrophic mice Dystrophic mice are notoriously difficult to breed and maintain using regular trios We have successfully practised alternative breeding schemes, of...
by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects
AIMS The current method of oral gavage in mice using gavage needles is a source of stress for the animals, potentially misleading or invalidating the results of an experiment. There are currently minimal alternatives to this method. We propose a stress-free...
by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects
AIMS Performing i.v. injections in rodents is a commonly needed task in research but challenging to learn in the beginning 3D-printed mouse tail models can be used to facilitate the learning process and reduce the number of practice injections needed on live animals...
by caitlin.sadowski@icloud.com | Jul 10, 2025 | Funded Projects
BACKGROUND With the Modernization Act 2.0 signed in early 2023, the FDA paves the way for more new drug applications without animal testing. This decision puts researcher and drug developers back into the drivers seat to quickly bring non-animal-based pre-clinical...
